It sounds more software. I would try the settings like you said, if that doesn't take, do a force restart, if that doesn't take, back it up, put it into dfu, restore. If all of that doesn't take, then we go for surgery. As replacing this cable is the most complicated repair on any iPhone, we'll try that last
Here's parts
[product|IF268-003]
Here's labor
https://d3nevzfk7ii3be.cloudfront.net/igi/ilKuESwYTY1KrpTP.large
Also, I realize this sounds ridiculous, check and make sure there isn't an S on the back, with a box around it. It makes a big difference. Practically all my customers don't know this, and don't understand why the repair cost is higher